Ace Your First Aid for the USMLE Step 1 2020 Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Medical (MD/DO) Students
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First Aid for the USMLE Step 1 2020 | Medical (MD/DO) School Study Aid
Hyperchylomicronemia (Type I Familial Dyslipidemia)
INHERITANCE
Autosomal Recessive
PATHOGENESIS
Lipoprotein Lipase Deficiency (LPL)
Altered Apolipoprotein C-II (Apo C-II)
Lab Findings
Increased Chylomicrons
Increased Cholesterol
Increased Triglycerides
Symptoms/Findings
Pancreatitis
Hepatosplenomegaly
No Increased Risk for Atherosclerosis
Eruptive/Pruritic Xanthomas
Milky White Appearance of Blood When Drawn
3 mins
Dysbetalipoproteinemia (Type III Familial Dyslipidemia)
INHERITANCE
Autosomal Recessive
PATHOGENESIS
Defective Apolipoprotein E (Apo E)
Lab Findings
Increased Chylomicrons
Increased VLDL
Symptoms/Findings
Premature atherosclerosis
Tuberoeruptive xanthomas
Palmar xanthomas
3 mins
Abetalipoproteinemia
Pathogenesis
Autosomal Recessive
Deficiency of Apolipoproteins B-48 and B-100
MTTP Gene Mutation
Clinical Features
Malabsorption
Steatorrhea
Failure to Thrive
Ataxia
Retinitis Pigmentosa
Spinocerebellar Degeneration
Diagnostic Workup
Lipid-Laden Enterocytes On Intestinal Biopsy
Acanthocytes
Decreased Plasma Choleserol and LDL Levels
Treatment
VItamin E (Alpha-Tocopherol)
3 mins
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