Ace Your First Aid for the USMLE Step 1 2019 Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Medical (MD/DO) Students

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First Aid for the USMLE Step 1 2019 Medical (MD/DO) School Study Aid


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Codon Overview
Characteristics
mRNA Read In Three Nucleotide Chunks
AUG Is Start Codon
Matching tRNA Anticodon
Amino Acid Specific (To Codon)
AUG Codes For Methionine
UAA, UAG And UGA Are Termination Codons
2 mins
Transcription Overview
Initiation
RNA Polymerase binds Promoter
Elongation
DNA Opens by Helicase
RNA Polymerase reads 3' to 5'
Nucleotides added to 3' end
Termination
Stem Loop Formation
Rho protein factor
2 mins
Eukaryotic Post Transcriptional Modification
Modifications in Nucleus
mRNA Splicing
Introns Cut Out
Exons spliced together
Alternate Splicing
5' Cap added
3' Poly A tail added
Transported to Cytosol
1 min
Translation: Initiation
Translation: Initiation
Ribosome Binds mRNA
Complex Reads 5' to 3'
AUG Start Codon
Initiation Complex Forms
GTP and Initiation Factor Bring Complex Together
Met-tRNA Binds P Site
tRNA With Bound Amino Acids Binds A Site
Amino Acid Chain Created in Elongation
2 mins
Translation: Elongation & Termination
Translation: Elongation
Amino Acid Chain Created
New Amino Acid-tRNA Enters A Site
GTP and Elongation Factors Help tRNA Enter A Site
Peptide Chain Binds to New Amino Acid
Peptide Chain-tRNA Moves to P Site
Free tRNA in P Site Moves to E Site
Translation: Termination
Stop Codon at A Site Causes Termination
Release Factors Help Complex Disassociate
Complex Falls Apart
2 mins

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