Fibroadenoma
- Most Common Benign Breast Tumor
 - Stromal Tumor
 - Women under 40
 - Small, firm mass
 - Sharp Edges
 - Increased tenderness and size with Estrogen
 - Biopsy
 
Intraductal Papilloma
- Bloody nipple discharge
 - Women 20-40 years old
 - Small tumor in lactiferous ducts
 - Occurs Centrally
 - Occurs Peripherally
 - Increased malignancy
 - Too Small to Palpate
 - Galactogram biopsy
 
Phyllodes Tumor
- Common in 40's
 - Large Palpable Mass
 - Benign
 - Rarely Malignant
 - Low-Grade Tumor
 - Leaf-Like
 - Stromal Tumor
 - Wide Resection
 
Breast Cancer Diagnosis
- Mammography
 - Ultrasound
 - MRI for High Risk Patients
 - Confirmed with Biopsy
 - Lymph Node Involvement
 - Receptor Positivity
 - Estrogen and Progesterone Receptors
 - HER-2
 
Breast Cancer Interventions
- Radiation or Chemotherapy
 - Hormonal Therapy
 - Tamoxifen
 - Lumpectomy
 - Mastectomy
 - Avoid BP and Injections Affected Arm
 - Hand Exercises
 - Grief Related to Body Image
 - Prosthetics
 - Reconstruction
 - Lymphedema
 
Paget Disease Of The Breast
- Spreading Ulceration At Nipple/Areola
 - Eczematous Or Vesicular Rash
 - Pruritus
 - Breast Mass
 - Bloody Or Yellow Discharge
 - Associated With Underlying Ductal Adenocarcinoma
 - Caused By Ductal Adenocarcinoma Cells Migrating To Surface
 - Biopsy
 - Bilateral Mammogram
 
Fibrocystic Changes of Breast
- Benign
 - Premenopausal Women
 - Bilateral, Multifocal Breast Pain
 - Ultrasound
 - Mammogram
 - Biopsy
 - Nonproliferative
 - Sclerosing Adenosis
 - Ductal Hyperplasia
 - Observation
 - Pharmacologic Interventions
 - Surgery
 
Lobular Carcinoma in Situ of Breast
- Noninvasive Malignancy
 - Absent Microcalcifications
 - Decreased E-Cadherin
 - Often Asymptomatic
 - Surveillance
 - Chemotherapy
 - Prophylactic Surgery
 
Invasive Ductal Carcinoma of Breast
- Most Common Breast Cancer
 - Firm, Palpable Mass
 - Nipple Retraction
 - Spiculated Margins
 - Microcalcifications
 - Stromal Glandular Cells
 - Surgery
 - Chemotherapy
 - Radiation
 
Inflammatory Carcinoma of Breast
- Invasive Malignancy
 - Invades Dermal Lymphatic Vessels
 - Mimics Mastitis and Paget Disease of Breast
 - Peau d'Orange
 - Breast Tenderness
 - Bloody Nipple Discharge
 - Poor Prognosis
 
Invasive Lobular Carcinoma of Breast
- Multifocal and Bilateral
 - Decreased E-Cadherin
 - "Single File" Cells
 - Often Asymptomatic
 - Surgery
 - Chemotherapy and Radiation
 
Ductal Carcinoma in Situ of Breast
- Noninvasive Malignancy
 - Terminal Duct Lobular Unit (TDLU)
 - Microcalcifications
 - Comedo Necrosis
 - Comedocarcinoma
 - High Grade
 - Dystrophic Calcification
 - Surgical Resection
 - Progresses to Invasive Breast Cancer