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Medicine (MD/DO)
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USMLE Step 2
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Infectious Disease
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Zoonotic Disorders

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Infectious Disease | Medicine (MD/DO) School Study Aid

Zoonotic Disorders
17 Picmonics to Learn | 35 mins
Lyme Disease
Mechanism
Transmitted by Ticks (Vector-borne)
Signs and Symptoms
Flu-like Symptoms
Bulls Eye Rash (Erythema Migrans)
Joint Pain and Stiffness
Facial Paralysis
Considerations
Antibiotics
Prevention
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2 mins
Borrelia burgdorferi
Characteristics
Lyme Disease
Spirochete
Dark-field Microscopy
Giemsa Stain
Silver Stain
White-footed Mouse
Ixodes Tick
Babesia
Anaplasmosis
Signs & Symptoms
Flu-like Symptoms
Erythema Migrans
Bulls Eye Rash
Bilateral Bell's Palsy
Conduction Defects
Arthropathy
Treatments
Doxycycline
Ceftriaxone
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3 mins
Rabies Virus
Characteristics
Enveloped
RNA Virus
SS Negative Linear
Helical
Bullet-Shaped Envelope
Binds to Acetylcholine Receptor
Retrograde Fashion
Migrates to Saliva
Diagnosis
Negri Bodies
Cytoplasmic Inclusions in Neurons
Purkinje Cells of Cerebellum
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2 mins
Rabies Symptoms and Animals
Characteristics
Bats, Skunks, and Raccoons (Inside United States)
Dog Bites (Outside United States)
Fever
Agitation
Paralysis
Hydrophobia
Photophobia
Considerations
Fatal If Not Treated
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1 min
Brucella
Characteristics
Gram-Negative
Coccobacillus
Unpasteurized milk
Goat cheese
Inside macrophages
Signs and Symptoms
Lymphadenopathy
Granulomas
Undulating fever
Treatment
Doxycycline
Gentamicin
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2 mins
Yellow Fever Virus
Characteristics
Flavivirus
RNA Virus
Enveloped
Icosahedral
SS Positive Linear
Transmitted By Aedes Mosquitos
Monkey or Human Reservoir
Signs and Symptoms
High fever
Jaundice
Black vomitus
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2 mins
Trypanosoma cruzi
Pathophysiology
Protozoa
Triatomine Bug
Kissing bug
Painless bite
Predominantly in South America
Symptoms
Chagas disease
Romana's sign
Dilated Cardiomyopathy
Megacolon
Megaesophagus
Diagnosis
Blood smear
Treatment
Nifurtimox
Benznidazole
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2 mins
Babesia
Characteristics
Protozoa
Ixodes Tick
Same vector as Borrelia
Northeastern US
Asplenia
Signs and Symptoms
Fever
Hemolytic Anemia
Diagnosis
Blood Smear
Maltese Cross
Treatments
Atovaquone
Azithromycin
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3 mins
Francisella tularensis
Mechanism
Contact with Infected Animals
Dermacentor Wood Tick
Deer Fly
Characteristics
Gram-Negative
Coccobacilli
Facultative Intracellular
Charcoal Yeast Agar with Cysteine and Iron
Signs and Symptoms
Ulceration
Fever
Painful Lymphadenopathy
Caseating Granulomas
Treatment
Streptomycin
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3 mins
Rocky Mountain Spotted Fever
Rickettsia rickettsii
Dermacentor Wood Tick
Endemic to East Coast
Fever
Headache
Rash Starts on Wrist and Ankle
Rash migrates towards the trunk
Thrombocytopenia
Hyponatremia
Elevated liver enzymes
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59 secs
Rickettsia
Need CoA and NAD
Rocky Mountain spotted fever
Typhus
Ehrlichiosis
Q fever
Arthropod vector
Fever
Headache
Rash
Weil-Felix reaction
Treatment doxycycline
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1 min
Trypanosoma Brucei
Characteristics
Protozoa
Trypanosoma Gambiense
Trypanosoma Rhodesiense
Tsetse Fly
Disease
Painful Bite
African Sleeping Sickness
Recurring Fever
Capacity for Antigenic Variation
Enlarged Lymph Nodes
Encephalitis
Treatment
Suramin for Blood-Borne Disease
Melarsoprol for CNS Penetration
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2 mins
Bartonella henselae
Characteristics
Gram-Negative
Pleomorphic
Bacillus
Signs and Symptoms
Cat Scratch Fever
Lymphadenopathy
Bacillary Angiomatosis
Patients with AIDS
Mimics Kaposi Sarcoma
Benign
Reactive Arthritis
Non-Caseating Granuloma
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2 mins
Mycobacterium leprae
Characteristics
Acid-Fast
Aerobic
Likes Cool Temperature
Diagnosis by Skin Biopsy or PCR
Lepromatous Leprosy
Th2 Response
Leonine Facies
Tuberculoid Leprosy
TH1 Response
Hypoesthetic Skin Plaques
Granulomatous Response
Treatment
Dapsone
Rifampin
Clofazimine
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2 mins
Ehrlichiosis
Characteristics
Intracellular Gram-Negative Rod
Lone Star Tick
Deer Reservoir
Clinical Features
Fever
Flu-like Symptoms
Rash is Rare
Diagnostic Workup
Antibody Testing
Pancytopenia
Monocytes with Cytoplasmic Morulae
Treatment
Doxycycline
Tetracycline
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2 mins
Leptospirosis and Weil's Disease
Epidemiology
Tropical Regions
Water Contaminated with Animal Urine
Characteristics
Leptospira interrogans
Spirochete
Hooked Shaped Ends
Clinical Features
Flu-like Symptoms
Conjunctival Suffusion
Photophobia
Weil's disease
Liver and Kidney Dysfunction
Jaundice
Hemorrhage
Anemia
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2 mins
Anaplasmosis
Characteristics
Ixodes Tick
Deer and Mice Reservoirs
Clinical Features
Flu-Like Symptoms
Fever
Rash is Rare
Diagnosis
Granulocytes with Cytoplasmic Morulae
Antibody Testing
Pancytopenia
Management
Doxycycline
Rifampin
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2 mins

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