Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Depression
- Anxiety
- Selective Serotonin Reuptake Inhibitors
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine
Fluoxetine (Prozac)
- Inhibits Reuptake of Serotonin
- Depression
- Sexual Dysfunction
- CNS Stimulation
- Weight Changes
- Serotonin Syndrome
- No MAO-Is
- No Anticoagulants / Antiplatelets
- Suicide Risk
- Delayed Onset of Action
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
- Depression
- Diabetic Peripheral Neuropathy
- Duloxetine
- Panic and Anxiety
- Venlafaxine
- Inhibits Reuptake of Serotonin and NE
- Hypertension
- Insomnia
- Nausea and Vomiting
- Decreased Libido
Bupropion
- Depression
- Smoking Cessation
- Increase Dopamine and NE
- Stimulant Side Effects
- Seizure
Tricyclic Antidepressants (TCAs) Overview
- Blocks Serotonin and NE Reuptake
- Lipid-soluble
- Adverse CNS Effects
- Anticholinergic
- Antihistamine
- Tri-C: Convulsion, Coma, Cardiotoxicity
- Blocks Alpha1 Receptors
Tricyclic Antidepressants (TCAs) Indications
- Major Depression
- Bedwetting
- Fibromyalgia
- OCD
- -Iptyline or -Ipramine Suffix
- Amitriptyline
- Desipramine
- Clomipramine
- Imipramine
- Nortriptyline
Tricyclic Antidepressant (TCA) Antidote
- Sodium Bicarbonate (NaHCO3)
Monoamine Oxidase Inhibitors (MAO-Is)
- Atypical Depression
- Increase Levels of Amine Neurotransmitters
- "Takes Pride In Shanghai"
- Tranylcypromine
- Phenelzine
- Isocarboxazid
- Selegiline
Monoamine Oxidase Inhibitor (MAOI) Contraindications
- Wine and Cheese
- Hypertensive Crisis
- Serotonin Drugs
- Serotonin Syndrome
Aripiprazole (Abilify)
- 2nd Generation Atypical Antipsychotic
- Schizophrenia
- Bipolar Disorder
- Depression
- Headache
- Dizziness
- Nausea and Vomiting
- Insomnia
- Anxiety
- Low Risk of Extrapyramidal Symptoms
- Lowest Risk of Weight Gain
Selective Alpha-2 Blockers
- Mirtazapine
- Depression Treatment
- Blocks Alpha2 Receptor
- Antagonist at 5-HT receptors
- Sedation
- Weight gain
- Increased Serum Cholesterol
Vortioxetine
- Inhibits Reuptake of Serotonin
- Major Depressive Disorder
- Nausea
- Sexual Dysfunction
- Anticholinergic Effects
- Sleep Disturbances
- Serotonin Syndrome