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Medicine (MD/DO)
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USMLE Step 1
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Pathology
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Ovarian Disorders

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Pathology | Medicine (MD/DO) School Study Aid

Ovarian Disorders
13 Picmonics to Learn | 15 mins
Polycystic Ovarian Syndrome (PCOS) Mechanism
Mechanism
Hyperinsulinemia Increases GnRH Pulse Frequency
Large Increase in LH
Small Decrease in FSH
Increased Androgen Production From Theca-Lutein Cells
Decreased Steroid Hormone-Binding-Globulin (SHBG) Causes Increased Free Testosterone
Obese Patients Have Increased Estrogen
Increased Risk of Endometrial Cancer
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2 mins
Polycystic Ovarian Syndrome (PCOS) Symptoms and Diagnosis
Symptoms
Most Common Cause of Infertility in Women
Amenorrhea
Acne
Hirsutism
Obesity
Diagnosis
Enlarged, Cystic Ovaries
LH:FSH Ratio of 3:1
"String of Pearls" on Ultrasound
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1 min
Polycystic Ovarian Syndrome (PCOS) Treatment
Weight Loss
Oral Contraceptives
Clomiphene Citrate
Anti-androgens
Cyclic Progesterone for Endometrial Protection
Metformin
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1 min
Fibromas
Non-germ cell tumor
Meigs Syndrome
Thecoma
Pulling sensation in groin
Spindle-shaped fibroblasts
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44 secs
Ovarian Cystadenoma
Non-germ cell tumor
Serous
Unilocular
Bilateral
Mucinous
Multilocular
Benign
Most Common
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49 secs
Ovarian Cystadenocarcinoma
Non-germ Cell Tumor
Mucinous
Peritoneal Spread
Serous
Psammoma Bodies
Bilateral
Malignant
Stromal Invasion
CA 125
BRCA-1 and Lynch Syndrome
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1 min
Brenner Tumor
Pathophysiology
Non-germ cell tumor
Transitional epithelium
Benign and unilateral
Coffee bean nuclei
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2 mins
Dysgerminoma
Germ-cell tumor
Most Common Malignant Germ Cell Tumor
Uniform Cells
Fried Egg Cells
hCG
LDH
Seminoma-like
Turner Syndrome
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2 mins
Yolk Sac Tumor
Germ-cell tumor
AFP
Aggressive Malignancy
Yellow, Friable Solid
Schiller-Duval Bodies
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43 secs
Teratoma
Germ-cell Tumor
Dermoid Cyst (Benign and Mature Teratoma)
Immature Teratoma (Malignant)
Struma Ovarii
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2 mins
Choriocarcinoma
Germ-cell tumor
Trophoblastic tissue
Hematogenous spread to lungs
Malignant
Theca-lutein cysts
Hydatidiform Mole
hCG
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59 secs
Granulosa Cell Tumor
Granulosa Cells
Non-germ cell tumor
Endometrial Carcinoma
Call-Exner bodies
Estrogen producing
Precocious Puberty
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43 secs
Krukenberg Tumor
Non-germ Cell Tumor
Lymphatic Spread to Ovaries
Metastasis
GI Malignancy
Mucin-secreting Signet Cell
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34 secs

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