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Medicine (MD/DO)
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USMLE Step 1
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Pathology
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Infectious Neurologic, Ophthalmologic & Otologic Disorders

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Pathology | Medicine (MD/DO) School Study Aid

Infectious Neurologic, Ophthalmologic & Otologic Disorders
14 Picmonics to Learn | 30 mins
Meningitis Assessment
Assessment
Nausea and Vomiting
Fever
Nuchal Rigidity
Severe Headache
Purpura
Seizures
Photophobia
Infants and Young Children
Opisthotonus Position
High-Pitched Cry
Bulging Fontanel
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2 mins
Meningitis Interventions
Drug Therapy
IV Antibiotics
Dexamethasone
Analgesics
Antipyretics
Considerations
Closely Monitor for Increased ICP
Bed Rest
Preventative Vaccinations
Droplet-Airborne Precautions
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2 mins
Mumps Virus
Characteristics
Paramyxovirus
Signs and Symptoms
Parotitis
Increased Serum Amylase
Orchitis
Oophoritis
Aseptic Meningitis
Pancreatitis
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59 secs
Toxoplasma gondii
Characteristics
Protozoa
Cysts in Meat or Cat Feces
Signs and Symptoms
Brain Abscess in HIV Patients
Ring-enhancing Brain Lesions
Crosses Placenta in Pregnant Women
Congenital TORCH Infection
Treatment
Pyrimethamine
Sulfadiazine
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2 mins
Mucor and Rhizopus
Characteristics
Fungi
Irregular Non-septate Hyphae
Branching Wide Angles over 90 degrees
Signs and Symptoms
Leukemic Patients
Proliferate due to excess ketones and glucose
Diabetic Ketoacidosis (DKA)
Rhinocerebral frontal lobe abscess
Penetrate cribriform plate into brain
Black Necrotic Eschars on Face
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2 mins
Herpes Simplex Virus (HSV)
Characteristics
Enveloped
Double Stranded DNA
Linear
Signs and Symptoms
Type 1 HSV
Gingivostomatitis
Keratoconjunctivitis
Encephalitis of Temporal Lobes
Latent in Trigeminal Ganglia
Type 2 HSV
Genital Vesicles
Neonatal Herpes
TORCHES
Latent in Sacral Ganglia
Diagnosis
Tzanck Test
Multinucleated Giant Cells
Cowdry A Inclusions
Treatment
Acyclovir
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2 mins
Clostridium tetani
Characteristics
Gram-Positive
Bacilli
Obligate Anaerobic
Exotoxin
Spore-Forming
Renshaw Cells in the Spinal Cord
Blocks Glycine and GABA Release
Signs and Symptoms
Spasms
Risus Sardonicus
Lockjaw
Opisthotonus
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3 mins
Rabies Virus
Characteristics
Enveloped
RNA Virus
SS Negative Linear
Helical
Bullet-Shaped Envelope
Binds to Acetylcholine Receptor
Retrograde Fashion
Migrates to Saliva
Diagnosis
Negri Bodies
Cytoplasmic Inclusions in Neurons
Purkinje Cells of Cerebellum
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2 mins
Rabies Symptoms and Animals
Characteristics
Bats, Skunks, and Raccoons (Inside United States)
Dog Bites (Outside United States)
Fever
Agitation
Paralysis
Hydrophobia
Photophobia
Considerations
Fatal If Not Treated
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1 min
Otitis Media Assessment
Red or Bulging Tympanic Membrane
Ear Pain
Pulling at Ear
Fever
Upper Respiratory Infection
Considerations
More Common in Young Children
Eustachian Tube Narrower
Conductive Hearing Loss
Smoking Increases Risk
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2 mins
Otitis Media Interventions
Antipyretics
Analgesics
Antibiotics
Irrigation
Position on Affected Side
Myringotomy
Tympanostomy Tube
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2 mins
Creutzfeldt-Jakob Disease (CJD)
Pathophysiology
Misfolded Prion Protein
Spongiform Encephalopathy
Subtypes
Sporadic Type
Familial Type
Variant Type
Iatrogenic Type
Clinical Manifestations
Rapidly Progressive
Dementia
Ataxia
Myoclonus
Diagnosis
Magnetic Resonance Imaging (MRI)
Increased Levels of 14-3-3 Protein
Periodic Sharp Waves On EEG
Management
Supportive Care
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4 mins
Poliomyelitis
Characteristics
Poliovirus
Picornavirus
Fecal-Oral Transmission
Destruction of Anterior Horn
Clinical Features
Flaccid Paralysis
Hyporeflexia
Fasciculations
Diagnosis
Elevated CSF Lymphocytes and Proteins
Normal CSF Glucose
Viral Culture or PCR
Management
Supportive Care
Vaccination
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3 mins
Herpes Zoster (Shingles)
Cause/Mechanism
Varicella-Zoster Virus
Assessment
Linear, Unilateral Rash Along a Dermatome
Pruritus
Postherpetic Neuralgia
Interventions
Acyclovir
Analgesics
Gabapentin
Considerations
Contagious Vesicles
Shingrix
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3 mins

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