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Pathology | Medicine (MD/DO) School Study Aid


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Infectious Gastrointestinal Disorders
26 Picmonics to Learn | 52 mins

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Gastroenteritis
Cause/Mechanism
Viruses
Bacteria
Food Intolerances
Assessment
Flu-Like Symptoms
GI Distress
Bloody Stool
Interventions
Oral Rehydration
Considerations
Self-Limiting
Prevention
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2 mins
Salmonella Typhi
Characteristics
Colonizes Gallbladder
Monocytic Immune Response
Symptoms
Typhoid Fever
Abdominal Pain
Rose Spots on Abdomen
Constipation Followed by Diarrhea
Treatments
Ceftriaxone
Fluoroquinolones
Considerations
Oral Vaccine - Live
IM Vaccine - Capsular Polysaccharide
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2 mins
Clostridium difficile
Characteristics
Gram-Positive
Bacillus
Anaerobe
Clindamycin and Ampicillin
Toxin A Enterotoxin
Damages Brush Border of Gut
Toxin B Cytotoxin
Damages Cytoskeletal Structure
Signs and Symptoms
Diarrhea
Pseudomembranous Colitis
Toxic Megacolon
Diagnosis
Detect Toxins in Stool
Treatment
Metronidazole
Vancomycin
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3 mins
Clostridium difficile (Clostridioides difficile) Treatments
Oral Vancomycin
Fidaxomicin
Metronidazole
Stool Transplant
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2 mins
E. coli Overview
Characteristics
Gram-Negative
Bacillus
Purple Colony with Metallic Green Sheen
Lactose-Fermenting
Pink on MacConkey Agar
Disease
Diarrhea
Lipid A Septic Shock
P Pili Pyelonephritis and Cystitis
K Capsule Neonatal Meningitis
K Capsule Pneumonia
H Antigen Flagella
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2 mins
EHEC (Enterohemorrhagic E. Coli)
Characteristics
O157:H7
Non-Sorbitol Fermenting
Hamburger Meat
Produces Shiga-Like Toxin
Gram-Negative
Lysogeny
Inactivates 60 S ribosome
Disease
Bloody Diarrhea
Hemolytic Anemia
Hemolytic Uremic Syndrome (HUS)
Acute Renal Failure
Thrombocytopenia
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2 mins
Shigella
Characteristics
Gram-Negative
Bacilli
Non Lactose Fermenting
White on Macconkey Agar
Oxidase Negative
Non H2S Producing
Day Care Centers
High Virulence
Replicates Intracellularly
Actin Rocket
Signs and Symptoms
Bloody Diarrhea
Shiga Toxin
Inhibits 60S Ribosome
Hemolytic Uremic Syndrome (HUS)
Hemolytic Anemia
Thrombocytopenia
Kidney Failure
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3 mins
Listeria Monocytogenes Characteristics
Characteristics
Gram Positive
Bacillus
Intracellular
Survives in Cold Temperature
Actin Rocket
Tumbling Motility
Catalase-Positive
Beta-Hemolytic
Only Gram-Positive with Endotoxin-Like Structure
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2 mins
Listeria Monocytogenes Disease
Signs and Symptoms
Soft Cheese
Pregnant Women Have Flu-Like Symptoms
Pregnant Women Have GI Symptoms
Granulomatosis Infantiseptica
Spontaneous Abortion
Meningitis
Monocytes in CSF
Treatment
Ampicillin
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2 mins
Norovirus
Characteristics
Calicivirus
RNA Virus
Non-enveloped
Icosahedral
SS Positive Linear
Symptoms
Acute Gastroenteritis
Treatment
Supportive Therapy
Considerations
Often found in Cruise Ships
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1 min
Rotavirus
Characteristics
Reovirus
Non-enveloped
Double-Stranded
RNA Virus
Linear
11 Segments
Triple Icosahedral Capsid
Most Common Cause of Diarrhea Worldwide
Villous Atrophy
Winter Months
Day Care Centers
Treatment
Oral Rehydration
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2 mins
Hepatitis A
Characteristics
Picornavirus
4 Week Incubation Period
Fecal-oral
Day Care Centers
Travel to Developing Countries
Signs and Symptoms
Usually Asymptomatic
Acute Disease
Jaundice
Fever
Vomiting
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2 mins
Hepatitis A (HAV) Assessment
Transmission
Fecal-Oral
Ingestion of Contaminated Food or Water
Incubation
4 Weeks
Assessment
Fever
General Malaise
Hepatomegaly
Considerations
Self-Limiting
Proper Hand Washing
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2 mins
Hepatitis B Virus Disease
Can turn chronic
< 10% of adults become chronic carriers
90% of newborns become chronic carriers
Cirrhosis
Hepatocellular carcinoma
Membranous Glomerulonephritis
Polyarteritis nodosa
Serum sickness like syndrome
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2 mins
Hepatitis B (HBV) Assessment
Transmission
Bodily Fluids
Blood Transmission
IV Drug Abusers
Incubation
Variable 1-6 Months
Assessment
Fever
Nausea and Vomiting
Hepatomegaly
Chronic Disease
Cirrhosis
Hepatocellular Carcinoma
Considerations
Vaccination
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2 mins
Hepatitis B Virus Characteristics
Hepadnavirus
Enveloped
Circular
Partially Double-stranded DNA
Has Reverse Transcriptase
IV Drug Use
Sex
Maternal fetal routes
3 month incubation period
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2 mins
Hepatitis C
Characteristics
Enveloped
RNA Virus
Flavivirus
Icosahedral
SS positive Linear
Clinical Features
Most Cases are Due to IV Drug Use
Turns to Chronic Hepatitis in Over 70% of Cases
Cirrhosis
Hepatocellular Carcinoma
Most Common Indication for Liver Transplantation
Associated With Type I MPGN
Porphyria Cutanea Tarda
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2 mins
Hepatitis C (HCV) Assessment
Transmission
Blood Transmission
High Risk Sex (rare)
IV Drug Abusers
Incubation
7 Weeks
Chronic Disease
Cirrhosis
Considerations
Barrier Protection
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2 mins
Clostridium botulinum
Characteristics
Bacillus
Gram-Positive
Anaerobe
Spore-Forming
Heat Labile Toxin
Inhibits Acetylcholine (Ach) Release at Neuromuscular Junction (NMJ)
Canned Food in Adults
Spores in Honey
Signs and Symptoms
Descending Flaccid Paralysis
Diplopia
Ptosis
Floppy Baby
Constipation
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2 mins
Staphylococcus aureus Disease
Skin Infections
Impetigo
Abscesses
Exfoliative Toxin
Scalded Skin Syndrome
Toxic Shock Syndrome (TSST 1)
Binds to MHC II and T Cell Receptor
Food Poisoning
Acute Bacterial Endocarditis
Pneumonia
Osteomyelitis
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2 mins
Bacillus Cereus Characteristics
Gram-Positive
Bacilli
Endospore Forming
B Hemolytic
Toxins and Enterotoxins
Reheated Rice
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1 min
Bacillus Cereus Disease
Signs and Symptoms
Emetic Form
Short Incubation (1-6 Hours)
Nausea and Vomiting
Diarrheal Form
Long Incubation (8-16 Hours)
Diarrhea and GI Pain
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2 mins
Entamoeba histolytica
Pathophysiology
Protozoa
Amebiasis
Ingestion of Cysts in Food and Water
Signs and Symptoms
Bloody Diarrhea
Flask-Shaped Ulcer
Liver Abscess
Anchovy Paste
RUQ Pain
Diagnosis
RBCs in Cytoplasm of Trophozoite
Cyst With Four Nuclei
Treatment
Metronidazole
Iodoquinol
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3 mins
Giardia lamblia
Characteristics
Protozoa
Ingestion of Cysts
Seen in Campers
Daycare Centers
Mental Hospitals
Infects Small Intestine
Signs and Symptoms
Bloating
Flatulence
Fatty Diarrhea
Diagnosis
Crescent-shaped Protozoa Adjacent to Epithelial Brush Border
Predisposed if Low IgA
Treatment
Metronidazole
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3 mins
Echinococcus Granulosus
Pathophysiology
Cestode (Tapeworm)
Ingestion of Eggs from Dog Feces
Hydatid Cysts in Liver
Fibrosis and Necrosis
Anaphylaxis if Antigens Released
Treatment
Albendazole
Surgical Removal
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1 min
Trypanosoma cruzi
Pathophysiology
Protozoa
Triatomine Bug
Kissing bug
Painless bite
Predominantly in South America
Symptoms
Chagas disease
Romana's sign
Dilated Cardiomyopathy
Megacolon
Megaesophagus
Diagnosis
Blood smear
Treatment
Nifurtimox
Benznidazole
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2 mins

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