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Medicine (MD/DO)
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USMLE Step 1
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Immunology & Oncology
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Immune Responses

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Immunology & Oncology | Medicine (MD/DO) School Study Aid

Immune Responses
9 Picmonics to Learn | 18 mins
Innate Immunity Cellular Response
Characteristics
Natural Killer Lymphocytes Attack Abnormal Cells
Neutrophils in Blood
Infected Cells Release Interferon
Complement Proteins Lyse Pathogens/Infected Cells
Dendritic Cells in Tissue
Macrophages in Tissue
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2 mins
Humoral Adaptive Immunity
Characteristics
B Cell Binds Free Floating Antigen
B Cell Presents Antigen to Helper T Cell
Helper T Cells Help B Cells Develop Antigen Specificity
Plasma B Cells Secrete Antibodies
Memory B Cells Cause Faster Secondary Response
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2 mins
Cell-mediated Adaptive Immune Response
Characteristics
Macrophages and Dendritic Cells Present Antigens
T Cell Develops Antigen Specificity
Regulatory T Cells Suppress Response
Memory T Cells Cause Faster Secondary Response
Cytotoxic T Cells Lyse Infected Cells
Infected Cells Present Antigen On Surface
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2 mins
Inflammatory Response
Pathogens Infect Tissue
Mast Cells Release Histamine
Histamine Dilates and Increases Capillary Permeability
Macrophages Engulf Pathogens
Macrophage Signals Cells With Cytokines
Responding Neutrophils Cross Capillary Wall
B And T Lymphocytes Arrive At Injury Site
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2 mins
Cancer Warning Signs (CAUTION)
CAUTION
Change in Bowel or Bladder Habits
A Sore That Does Not Heal
Unusual Bleeding or Discharge
Thickening or Lump in the Breast or Elsewhere
Dyspepsia (Indigestion)
Obvious Change to Warts or Moles
Nagging Cough
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1 min
Hallmarks of Cancer
Growth Signals
Growth Signal Self-sufficiency
Anti-growth Signal Insensitivity
Control of Replication
Evasion of Apoptosis
Limitless Replication
Progression/Spread
Angiogenesis
Tissue Invasion
Metastasis
Warburg Effect
Immune Evasion
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2 mins
Allergic Contact Dermatitis
Pathophysiology
Type IV Hypersensitivity
Physical Contact with Allergen
Nickel
Neomycin
Poison Ivy
Clinical Features
Urticaria
Pruritus
Erythematous, Vesicular
Diagnosis
Patch Testing
Treatment
Avoid Cause
Topical Hydrocortisone
Antihistamines
Cool Water Soaks
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2 mins
Immunoglobulin Isotypes
IgM
Primary Immune Response
Cold Agglutinin Autoimmune Hemolytic Anemia (C-AIHA)
IgG
Crosses Placenta
Warm Agglutinin Autoimmune Hemolytic Anemia (W-AIHA)
IgA
Released in Secretions, Mucosal Fluids, and Breast Milk
IgD
IgE
Against Parasitic Worms
Allergic Reaction
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3 mins
Graft Versus Host Disease
Pathophysiology
Graft T Cell Sensitization Against Host MHC Antigens
Graft Recognizes Host as "Foreign"
Type IV Hypersensitivity
Signs and Symptoms
Diffuse Maculopapular Rash
Jaundice
Diarrhea
Hepatosplenomegaly
Associations
Severe Immunocompromised Patients
Bone Marrow and Liver Transplantation
Transfusion of Non-irradiated Blood
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2 mins

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