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PANCE Prep Pearls: 2nd Ed. (2017)
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Page 66 -

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PANCE Prep Pearls: 2nd Ed. (2017) | Physician Assistant (PA) School Study Aid

Page 66 -
4 Picmonics to Learn | 9 mins
Heparin Induced Thrombocytopenia (HIT)
Pathophysiology
5-10 Days After Heparin Exposure
Heparin-Platelet Factor 4 Complex
Autoantibodies Form Against Complex
Heparin-Platelet Factor 4-Antibody Complex Binds Platelets
Platelet Aggregation
Procoagulant Release
Symptoms
Thrombocytopenia
Diagnosis
Serotonin Release Assay (SRA)
Treatment
Stop Heparin, Start Direct Thrombin Inhibitor
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2 mins
Wells' Criteria for Pulmonary Embolism
Scoring
Clinical Symptoms of DVT (+3)
Pulmonary Embolism Most Likely Diagnosis (+3)
Tachycardia (+1.5)
Immobilization > 3 Days (+1.5)
Previous DVT or PE (+1.5)
Hemoptysis (+1)
Malignancy (+1)
Probability
> 6 = High
2-6 = Moderate
< 2 = Low
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3 mins
Deep Vein Thrombosis (DVT) Characteristics
Mechanism
Virchow's Triad
Venous Stasis
Endothelial Damage
Hypercoagulability
Symptoms
Tenderness
Homan's Sign
Warmth
Redness
Swelling
Asymptomatic
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1 min
Deep Vein Thrombosis (DVT) Management
Diagnosis
Compression Ultrasound (CUS) with Doppler
D-Dimer
Contrast Venography
Treatment
IVC Filter
Heparin for Acute Management
Warfarin for Long-term Management
Thrombectomy/Thrombolysis
Stockings
Walking
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4 mins

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