Master Quad Screen Results Interpretation with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Quad Screen Results Interpretation

4 Screen display
Picmonic
Markers to assess fetal well-being are often combined into a quad screen because their power lies in their use together. The quad screen views inhibin A, hCG, AFP and estriol levels to assess the fetus' risk of chromosomal abnormalities. Using these markers we can predict specific defects, like Down syndrome, which has a high hCG and inhibin A, or Turner syndrome, which has a very high hCG and inhibin A. Edward syndrome has a low hCG, estriol, and AFP. In Patau syndrome, AFP is normal.
8 KEY FACTS
MARKERS
AFP
Air Force Pilot

Alpha-fetoprotein (AFP) is found in both fetal serum and also amniotic fluid. This protein is produced early in gestation by the fetal yolk sac and then later in the liver and gastrointestinal tract. This value is then combined with other markers, as well as the mothers' age and family history to assess a risk for abnormalities.

Estriol
Extra-terrestial

Estriol is only produced in significant amounts during pregnancy, as it is made by the placenta. If levels of unconjugated estriol are abnormally low in a pregnant woman, this may indicate chromosomal or congenital anomalies like Down syndrome or Edward syndrome.

hCG
Hard-Core-Gnome

Human chorionic gonadotropin (hCG) is a hormone produced by a portion of the placenta following implantation. It is used to detect pregnancy, and diagnose and monitor germ cell tumors, as well as gestational trophoblastic diseases. It is combined with other markers to assess fetal disorders in the quad test.

Inhibin A
Inhibiting-chains Apple-tree

Inhibin is produced in the gonads, pituitary gland, placenta, corpus luteum and other organs. It plays a role in regulating FSH, but when combined with other serological markers, it is useful in screening for fetal disorders and aneuploidies.

ANEUPLOIDIES
Down Syndrome = HIgh
Child with Down Syndrome says HI

There is a high probability of Down syndrome with quad screen results showing low AFP, low estriol, high hCG, and high inhibin A. This can be recalled with "HI," representing high hCG and inhibin A.

Turner Syndrome = Very HIgh
Turnip says HI

There is a high likelihood of Turner syndrome in the fetus with quad screen results showing decreased AFP, decreased estriol, very high hCG, and very high inhibin A. The mnemonic Turner is "very high" represents a very high hCG and inhibin A.

Edward Syndrome = Low HEAp
Edward in a low HEAp

Quad screen results show a very low hCG, low estriol, and low AFP. These results are predictive of Edward syndrome. The mnemonic "Edward is a low HEAP" corresponds with low hCG (H), low estriol (E), and low AFP (AP). Inhibin A is usually normal in Edward syndrome.

Patau Syndrome = AFP is Normal
Paddles from Normal Air-Force-Pilot

Quad screen results showing a normal estriol, normal hCG, normal inhibin A, and normal AFP are indicative of Patau syndrome.

Unlock all 8 facts & definitions with Picmonic Free!

JOIN FREE

Take the Quad Screen Results Interpretation Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.