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Biochemistry | Medicine (MD/DO) School Study Aid

Aerobic Respiration

Mitochondrial Matrix

2 Pyruvate

Pyruvate Decarboxylation

2 NADH

2 Acetyl-CoA

Krebs Cycle

6 NADH

2 FADH2

2 Substrate Level ATPs

1 min

Anaerobic Respiration

Cytosol

Glucose

Glycolysis

Substrate-level Phosphorylation

2 NADH

2 Net ATP

2 Pyruvate

Fermentation

NAD+ Regeneration

Waste Byproduct

2 mins

Oxidative Phosphorylation

Inner Mitochondrial Membrane

Electron Transport Chain

Oxygen is Final Electron Acceptor

Proton Pump

Proton Motive Force

ATP Synthase

1 NADH 3 ATP

1 FADH2 2 ATP

2 mins

Energy Releasing Pathways: Accounting

Anaerobic Respiration

2 ATP

2 NADH

Aerobic Respiration

8 NADH

2 FADH2

2 ATP

Oxidative Phosphorylation

34 ATP

2 ATP Lost

36 Net Total ATP

2 mins

Enzyme Types

Lyases

Hydrolases

Transferases

Isomerases

Oxidoreductases

Ligases

1 min

Competitive Inhibition

Reversible Inhibition

Constant Vmax

Substrate Competes With Inhibitor For The Active Site

Inhibition Increases Km

1 min

Non-Competitive Inhibition

Reversible Inhibition

Substrate Freely Binds The Active Site

Inhibitor Strongly Binds Allosteric Site

Km Constant

Enzyme Has Different Conformational Form

Low Vmax

2 mins

Lipoprotein Functions

Chylomicron

Carries Dietary TGs to Peripheral Tissues

VLDL

Carries Hepatic TGs to Peripheral Tissue

IDL

Carries TGs and Cholesterol to Liver

LDL

Carries Hepatic Cholesterol to Peripheral Tissues

HDL

Returns Excess Cholesterol from Peripheral Tissues to Liver

2 mins

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