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Remember metformin, also known by its trade name glucophage, as a meat-farmer who becomes very lonely after he runs out of his insecticide. This medication works by decreasing glucose production, shown by the down-arrow glue, and increasing insulin sensitivity, the up-arrow insect-syringe. It is recommended for the treatment of type 2 diabetes, shown by the dyed-bead pancreas in a tutu, due to its mechanism of action. It can also be used in&nbsp;polycystic ovary syndrome (PCOS), shown by the peacock with PCOS. This syndrome is characterized by excess androgens and increased insulin resistance, thus metformin has been found to be effective in treating PCOS, as it increases the sensitivity of insulin. Side effects of metformin include GI distress, shown by the GI flare-gun, which includes symptoms such as nausea and diarrhea. It can also cause a decreased appetite, shown by the X on the mouth, which can lead to weight loss. And while it is a rare side effect, lactic acidosis, shown by the lake of acidic-lemon, can result from using metformin and is indicative of drug toxicity. Considerations include holding metformin 1-2 days before the use of IV contrast agents, represented by the IV-bag and contrasting-con, as IV contrast agents contain iodine, which can promote renal failure and further exacerbate lactic acidosis. This con is holding up an alcoholic-martini, limiting its consumption as those taking metformin should limit alcohol consumption because this can promote and intensify metformin induced lactic acidosis.&nbsp; So let&rsquo;s review. Metformin functions by decreasing glucose production and increasing insulin sensitivity. It is recommended for the treatment of type 2 diabetes and polycystic ovary syndrome (PCOS). Metformin is associated with minimal side effects but includes GI distress, decreased appetite, and possible lactic acidosis. IV contrast agents and alcohol intake should be used with caution when metformin is administered.&nbsp;

educational

story

meat farmer.png

glow.png

meats.png

metformin.png

Meat-farmer

Metformin (Glucophage)

Antidiabetic Agents

Mechanism

down arrow glue.png

gear.png

Down-arrow Glue

Decrease Glucose Production

What mechanism of action or pharmacological action is best associated with metformin (Glucophage)?

up arrow insect syringe crying.png

Up-arrow Insect-syringe Crying

Increase Insulin Sensitivity

Indications

dyed bead pancreas (2) tutu.png

crosshair.png

oldguy.png

Dyed-bead Pancreas in a (2) Tutu

Type 2 Diabetes

Which of the following is a disease or disorder most likely associated with metformin (Glucophage)?

peacock PCOS.png

Peacock with PCOS

Polycystic Ovary Syndrome (PCOS)

Side Effects

fx.png

GI Flare-gun

GI Distress

Which of the following is most likely a side effect associated with metformin (Glucophage)?

x on mouth.png

boosh.png

not in my mouth pancreas.png

X on Mouth

Decreased Appetite

lake of acid.png

Lake of Acidic-lemon

Lactic Acidosis

Considerations

IV bag Contrasting con.png

IV-bag and Contrasting-con

IV Contrast

Which of the following is a consideration when administering metformin (Glucophage)?

limiting alcoholic martini.png

you cant has.png

Limiting Alcoholic-martini

Limit Alcohol Consumption

Which of the following are medication instructions or patient education points associated with metformin (Glucophage)?

Brunner & Suddarth's Textbook of Medical-Surgical Nursing, 13th Edition

Family Nurse Practitioner Certification Intensive Review 2nd Edition, Leik

First Aid for the USMLE Step 1 2017

First Aid for the USMLE Step 1 2018

Ignatavicius Medical-Surgical Nursing, 9th Edition

Lilley, Rainforth Collins & Snyder, Pharmacology and the Nursing Process, 8th Ed.

Master The Boards USMLE Step 2 CK, 3E

Maternity and Women's Health Care, 11th Edition (Elsevier)

Medical-Surgical Nursing, 10th Ed, Lewis, Dirksen, Heitkemper, & Bucher

Medical-Surgical Nursing, 9th Ed, Lewis, Dirksen, Heitkemper, & Bucher

NP - Certification Examination and Practice Preparation 4th Edition, Fitzgerald

PANCE Prep Pearls: 1st Ed, 2014

PANCE Prep Pearls: 2nd Ed, 2017

Pharmacology and the Nursing Process 7e, Lilley, Rainforth Collins, Snyder, 2014

Pharmacology and the Nursing Process 8e, Lilley, Rainforth Collins, Snyder, 2017

Remember Metformin as a Meat-farmer who becomes very lonely after he runs out of his insecticide, Glue, and an increase of Insect-syringes overrun his farm. He decides to try his luck at online dating and tries Farmersonly.com. He gets hooked up with this cute Dyed-bead Pancreas in a Tutu. On their first date, he serves her the most expensive and rare meat on his farm, a Peacock with PCOS. Unfortunately though, the Pancreas is a vegetarian. I guess she was hoping for a corn farmer. &nbsp;She takes on bite of the peacock and her GI jumps out of her body with a Flare-gun and she gets an X on her Mouth because she is not going to eat anymore of that horrid meat. Then she runs and jumps into a Lake of Acidic-lemon to get away from the awful farmer. Now Meat-farmer is even more depressed. Not only is his farm failing, but his love life is in shambles. He turns to drink and goes to a bar manned by the IV-bag and Contrasting-con. However, he cuts the poor farmer off and takes away the Alcoholic-martini. Poor little Meat-farmer, I guess you reap what you sow.

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Picmonic NCLEX Question of the Day 09/20/2022

Picmonic NCLEX® Question of the Day

Today you are working on a floor you are not familiar with. You are taking care of a sweet, 70 year old grandma. She is scheduled for a CT scan involving the use of IV contrast. Which of the following medications should be withheld?

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