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Fluoxetine, known by its trade name Prozac, is part of a class of drugs known as serotonin reuptake inhibitor or SSRI, and can be remembered by the flute-ox playing his magical music for the town to hear. This drug works by inhibiting the reuptake of serotonin, shown by the inhibiting-chains on the silver-tonic reuptake-tube. It is used for the treatment of depression, shown by the depressed-emo holding on to the serotonin. Side effects include sexual dysfunction, the limp weiner, CNS stimulation, shown by the CNS-brain with stim-mule drink, and weight gain, the up-arrow scale. A rare but serious side effect of this drug is serotonin syndrome, the silver-tonic savage, which can lead to hypertension, autonomic instability, rigidity, and myoclonus. Because of this, concurrent medications like MAO-Is should not be given, shown by the caution-tape around MAO with inhibiting-chains. Additionally, patients should refrain from using anticoagulants or antiplatelets, shown by the caution-tape around ant-tie-clogs and ant-tie-plates, as this can increase the risk of GI bleeding. An important consideration to keep in mind is that during the initial phase of receiving this drug, suicide risk increases, shown by the suicidal-jumper on the risk bridge. Patients should be educated not to expect immediate effects with this medication, as there is a delayed onset of action, shown by the delayed on-switch, as SSRIs often take 1-3 weeks to reach therapeutic effects. So let&rsquo;s recap. Fluoxetine or Prozac works by inhibiting reuptake of serotonin and is commonly used for the treatment of depression. Side effects include sexual dysfunction, CNS stimulation, weight gain, and serotonin syndrome. Contraindications include MAO-Is, anticoagulants, and antiplatelets. There is an increase in suicide risk when first starting this med with a delayed onset of action.

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story

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Fluoxetine (Prozac)

Psych Pharm I

Selective serotonin reuptake inhibitors

SNRIs, Serotonin Antagonists and SSRIs – Antidepressants

Mechanism of Action

inhibiting chains on silver tonic reuptake tube.png

mechanism.png

Inhibits Reuptake of Serotonin

What mechanism of action or pharmacological action is best associated with Fluoxetine (Prozac)?

Indications

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indication.png

Depression

Which of the following is an indication for Fluoxetine (Prozac)?

Side Effects

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Sexual Dysfunction

Which of the following is a notable side effect of Fluoxetine (Prozac)?

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CNS Stimulation

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Weight Gain

Weight Changes

silver tonic savage.png

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Serotonin Syndrome

Contraindications

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No MAO-Is

Which of the following is an important consideration for a patient taking Fluoxetine (Prozac)?

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No Anticoagulants / Antiplatelets

Considerations

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Suicide Risk

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Delayed Onset of Action

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The flute-ox is like a magical nymph, and it appears at these ancient ruins every now and then, using its melody to summon depressed-emo's from their meloncholy. &nbsp;It does this by wrapping inhibiting-chains around the silver-tonic reuptake-tube, and for a single night, all the silver-tonics of the world are free to lead their respective depressed-emo's towards happiness, where they dance hand in hand around the flute-ox. &nbsp;But. &nbsp;And this is a big but. &nbsp;Much like the story of Pinocchio, where bad little boys travel to a place where they can have their fun, the fun comes with a price. &nbsp;While those bad boys were turned into donkey's, any depressed-emo who stays for too long will transform into something else entirely. &nbsp;The side effects first start when they take a breather from dancing, and sit down to enjoy the complimentary limp weiners, and wash them down with a stim-mule energy drink, for CNS stimulation during the all night dance party. &nbsp;The emo's are intoxicated by the melodies of the flute-ox, and they go on dancing. &nbsp;But it isn't long before they look in the mirror, and realize they've put on some weight. &nbsp;They start to ask themseves, "How long have I been here? &nbsp;I feel strange." &nbsp;That's when the price for their jovial mood becomes apparent. &nbsp;They morph into a silvery beast, a silver-tonic savage to be precise, and their bottled rage is released unto the world. &nbsp;The world leaders do what they can to minimize the damage by cordoning off the area with caution-tape. &nbsp;Ant-tie-clogs and ant-tie-plates run for their lives. &nbsp;But one world leader, Mao, is slowed by his inhibiting-chains, and the outcome is grim. &nbsp;The silver-tonic savage devours him whole. &nbsp;The emo awakes, mournful in the morning, fully aware of what he's done, as he picks gross little pieces of Mao from between his teeth. &nbsp;The guilt is too much to handle. &nbsp;He finds the nearest bridge and decides he must jump. &nbsp;But this suicide, he declares, will be considerate of others. &nbsp;He flips an on-switch to delay any traffic attempting to cross the bridge. &nbsp;And then, he says goodbye cruel world, and jumps. &nbsp;But the bridge is literally like 2 feet over the water, so in the end, after jumping, the emo finds purpose. &nbsp;In the flute. &nbsp;And he spends the rest of his days spreading happiness throughout the world through music.

Inquire about recent use of MAOI medications.

The medication may cause an increase in sexual desire.

The medication may take several weeks to take effect.

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Picmonic NCLEX Question of the Day 12/17/2021

Picmonic NCLEX® Question of the Day

The nurse is providing education to a patient about taking the medication fluoxetine. Which of the following should the nurse include in his or her education? Select all that apply:

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